Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer

Publication date

2018-04-05

Authors

van Son, Marieke
Peters, MaxISNI 0000000460018149
Moerland, RienISNI 0000000388861405
Noteboom, Juus LISNI 000000039196494X
Eppinga, Wietse S.C.ISNI 0000000389239685
Fajardo, Raquel Dávila
Lagendijk, J J WISNI 0000000393637862
van der Voort van Zyp, Jochem R NISNI 0000000393775683

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Abstract

Prostate cancer recurrences are common, even with twenty-first-century primary prostate cancer treatment modalities. The most common salvage treatment is (delayed) hormonal therapy, which is often associated with serious side-effects. Due to the risk of significant toxicity, whole-gland targeted salvage treatments remain unpopular. Consequently, developments in focal therapies have arisen. Magnetic resonance imaging (MRI)-guided focal salvage high-dose-rate brachytherapy (HDR-BT) is a novel treatment aiming for minimal toxicity in recurrent prostate cancer patients. Repeating focal treatment could, therefore, be possible in case of post-salvage recurrence. We report the case of a 77-year-old man who underwent repeat focal HDR-BT.

Keywords

prostate cancer, recurrence, brachytherapy, salvage therapy, interventional magnetic resonance imaging, Journal Article

Citation

Van Son, M J, Peters, M, Moerland, M A, Noteboom, J L, Eppinga, W S, Davila Fajardo, R, Lagendijk, J & Van der Voort van Zyp, J R 2018, 'Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer', Curēus, vol. 10, no. 4, e2429. https://doi.org/10.7759/cureus.2429