CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study
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Publication date
2017-02
Authors
Pallesen, Lars P.
Khomenko, Andrei
Dzialowski, Imanuel
Barlinn, Jessica
Barlinn, Kristian
Zerna, Charlotte
van der Hoeven, Erik J R J
Algra, Ale
Kappelle, Jaap
Michel, Patrik
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Document Type
Article
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taverne
Abstract
Background: Coma is associated with poor outcome in patients with basilar artery occlusion. Aims: We sought to assess whether the posterior circulation Acute Stroke Prognosis Early CT Score and the Pons-Midbrain Index applied to CT angiography source images predict the outcome of comatose patients in the Basilar Artery International Cooperation Study. Methods: Basilar Artery International Cooperation Study was a prospective, observational registry of patients with acute basilar artery occlusion with 48 recruiting centers worldwide. We applied posterior circulation Acute Stroke Prognosis Early CT Score and Pons-Midbrain Index to CT angiography source images of Basilar Artery International Cooperation Study patients who presented with coma. We calculated adjusted risk ratios to assess the association of dichotomized posterior circulation Acute Stroke Prognosis Early CT Score (≥8 vs.
Keywords
Basilar artery occlusion, coma, CTA source images, imaging scores, ischemic stroke, thrombolysis, Review, Taverne, Neurology, Journal Article, Multicenter Study, Observational Study
Citation
Pallesen, L P, Khomenko, A, Dzialowski, I, Barlinn, J, Barlinn, K, Zerna, C, van der Hoeven, E J R J, Algra, A, Kapelle, L J, Michel, P, Bodechtel, U, Demchuk, A M, Schonewille, W & Puetz, V 2017, 'CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study', International Journal of Stroke, vol. 12, no. 2, pp. 145-151. https://doi.org/10.1177/1747493016669886