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First contact(in): The complete structure of contactin 2

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PIIS0969212624003721.pdf (2.2 MB)

Publication date

2024-10-03

Authors

Chataigner, Lucas M.P.
Janssen, BertISNI 0000000419421614

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DOI

https://doi.org/10.1016/j.str.2024.09.003

Document Type

Article

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Utrecht University Repository
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taverne

Abstract

In this issue of Structure, Fan et al.1 report the structure of the full contactin 2 ectodomain, representing the first for the contactin family. The work reveals six immunoglobulin domains are essential for intercellular interactions, explores differences in proposed contactin 2 homodimerization mechanisms, and provides an updated model for contactin 2 organization on and between cells.

Keywords

Taverne, Structural Biology, Molecular Biology

Citation

Chataigner, L M P & Janssen, B J C 2024, 'First contact(in) : The complete structure of contactin 2', Structure (London, England : 1993), vol. 32, no. 10, pp. 1545-1547. https://doi.org/10.1016/j.str.2024.09.003

URI

https://dspace.library.uu.nl/handle/1874/473582