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Everything has its time: Id2 clocks embryonic specification of Lgr5+ gut stem cells

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Publication date

2017-04-03

Authors

Kretzschmar, Kai
Clevers, HansISNI 0000000043961208

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DOI

https://doi.org/10.15252/embj.201796482

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Comment

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taverne

Abstract

While adult intestinal stem cells and their niche are well characterised, their developmental specification is still poorly understood. In this issue of The EMBO Journal, Nigmatullina et al (2017) show that maturation of Lgr5+ progenitors in the small intestinal epithelium during murine embryonic development is controlled by the transcription factor Id2.

Keywords

Cell Differentiation, Humans, Receptors, G-Protein-Coupled, Stem Cells, Journal Article, Comment, Taverne, General Neuroscience, Molecular Biology, General Biochemistry,Genetics and Molecular Biology, General Immunology and Microbiology

Citation

Kretzschmar, K & Clevers, H 2017, 'Everything has its time : Id2 clocks embryonic specification of Lgr5 + gut stem cells', EMBO Journal, vol. 36, no. 7, pp. 837-839. https://doi.org/10.15252/embj.201796482

URI

https://dspace.library.uu.nl/handle/1874/361517