Macrophage vesicles in antidiabetic drug action
Publication date
2024-05
Authors
Stienstra, Rinke
Kalkhoven, Eric
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taverne
Abstract
Thiazolidinediones (TZDs) are potent insulin-sensitizing drugs, but their use is accompanied by adverse side-effects. Rohm et al. now report that TZD-stimulated macrophages release miR-690-containing vesicles that improve insulin sensitization and bypass unwanted side-effects.
Keywords
Taverne, Internal Medicine, Endocrinology, Diabetes and Metabolism, Physiology (medical), Cell Biology
Citation
Stienstra, R & Kalkhoven, E 2024, 'Macrophage vesicles in antidiabetic drug action', Nature metabolism, vol. 6, no. 5, pp. 785-786. https://doi.org/10.1038/s42255-024-01030-x