MR imaging for accurate prediction of outcome after perinatal arterial ischemic stroke: Sooner not necessarily better
Files
Publication date
2017-07
Authors
Wagenaar, Nienke
van der Aa, Niek E.
Groenendaal, Floris
Verhage, Lianne
Benders, Manon J.N.L.
de Vries, Linda S.
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
taverne
Abstract
BACKGROUND: Involvement of the corticospinal tracts after perinatal arterial ischemic stroke (PAIS) is strongly correlated with adverse motor outcome. METHODS: Two full-term infants with PAIS, with two early MRI scans available, are reported. RESULTS: Diffusion weighted imaging (DWI)-MRI, performed within 24 h following onset of seizures and repeated 48 h later, clearly showed restricted diffusion within the middle cerebral artery territory on both MRIs, but clear patterns of signal intensity changes in the descending corticospinal tracts on the second MRI only. CONCLUSION: Since involvement of the corticospinal tracts is essential for prediction of motor outcome, we may need to reconsider optimal timing of MR imaging for prediction of neurodevelopmental outcome after PAIS.
Keywords
Corticospinal tract, MRI, Neonate, PAIS, Stroke, Wallerian, Taverne, Journal Article
Citation
Wagenaar, N, van der Aa, N E, Groenendaal, F, Verhage, C H, Benders, M J N L & de Vries, L S 2017, 'MR imaging for accurate prediction of outcome after perinatal arterial ischemic stroke : Sooner not necessarily better', European Journal of Paediatric Neurology, vol. 21, no. 4, pp. 666–670. https://doi.org/10.1016/j.ejpn.2017.04.002