Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on "First-In-Man" Treatments
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Publication date
2018-04-05
Authors
Winkel, D
Bol, G H
Kiekebosch, Ilse H
van Asselen, B
Kroon, Petra S
Jürgenliemk-Schulz, Ina M.
Raaymakers, Bas
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Abstract
The superior soft tissue contrast provided by magnetic resonance (MR) images on the 1.5T MR-linac allows for the incorporation of patient anatomy information. In this retrospective case study, we present the simulated dosimetric effects and timings of full online replanning as compared to the five plan adaptation methods currently available on the 1.5T MR-linac treatment system. For this case, it is possible to create treatment plans with all six methods within a time slot suitable for an online treatment procedure. However, large dosimetric differences between the plan adaptation methods and full online replanning are present with regards to target coverage and dose to organs at risk (OARs).
Keywords
mr-linac, adaptive planning, adaptive radiotherapy, online replanning, lumbar spine bonemetastases, mr-guided-rt, mr-igrt, mr guided radiotherapy
Citation
Winkel, D, Bol, G H, Kiekebosch, I H, Van Asselen, B, Kroon, P S, Jürgenliemk-Schulz, I M & Raaymakers, B W 2018, 'Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on "First-In-Man" Treatments', Curēus, vol. 10, no. 4, e2431. https://doi.org/10.7759/cureus.2431