Cross-cultural treatment preferences: a call for diversity in drug development

Publication date

2025

Authors

Dijkgraaf, Dana M
Kiani, Pantea
Zijlstra, Maureen N
Verster, Joris CORCID 0000-0002-6455-2096ISNI 0000000076939752

Editors

Advisors

Supervisors

Document Type

Article
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License

cc_by_nc_nd

Abstract

Patient preferences for treatment characteristics-such as dosage form, taste, smell, and ingredients-play a key role in adherence, yet these preferences differ widely across cultures and are frequently overlooked in pharmaceutical development. Prescription medicines must meet strict safety and effectiveness standards, restricting flexibility, whereas over-the-counter supplements allow more freedom, though often without proven benefits. Developing diverse formulations is expensive and time-consuming, and patients need clear guidance to make informed choices without feeling overwhelmed or questioning their doctors. This tension highlights a disconnect between patient desires, scientific validation, and practical feasibility. We urge healthcare providers, pharmaceutical companies, and patients to engage in dialogue to discuss patient preferences and diversity in drug development. By creating treatments that reflect cultural needs and improving patient education, adherence and equity in healthcare can improve, provided the scientific, economic, and logistical hurdles are addressed effectively.

Keywords

Drug development, compliance, dosage form, ingredients, patient preferences, treatment adherence, General Medicine

Citation

Dijkgraaf, D M, Kiani, P, Zijlstra, M N & Verster, J C 2025, 'Cross-cultural treatment preferences : a call for diversity in drug development', Current Medical Research and Opinion, vol. 41, no. 6, pp. 1047-1051. https://doi.org/10.1080/03007995.2025.2537298