Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer
Publication date
2018-12-01
Authors
Severson, Tesa M.
Kim, Yongsoo
Joosten, Stacey E.P.
Schuurman, Karianne
van der Groep, Petra
Moelans, CB
Ter Hoeve, Natalie D.
Manson, Quirine F.
Martens, John W.
Van Deurzen, Carolien H.M.
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Document Type
Article
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Abstract
Male breast cancer (MBC) is rare and largely hormonally driven. Here, the authors examine the action of steroid hormone receptors in male and female breast cancers and find gender selective hormone receptor action that associates with the survival of MBC patients.
Keywords
General Chemistry, General Biochemistry,Genetics and Molecular Biology, General Physics and Astronomy
Citation
Severson, T M, Kim, Y, Joosten, S E P, Schuurman, K, Van Der Groep, P, Moelans, C B, Ter Hoeve, N D, Manson, Q F, Martens, J W, Van Deurzen, C H M, Barbe, E, Hedenfalk, I, Bult, P, Smit, V T H B M, Linn, S C, Van Diest, P J, Wessels, L & Zwart, W 2018, 'Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer', Nature Communications, vol. 9, no. 1, 482. https://doi.org/10.1038/s41467-018-02856-2