Food allergy and food-based therapies in neurodevelopmental disorders
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Publication date
2014-01-01
Authors
de Theije, C.G.M.
Bavelaar, Bas M.
Lopes da Silva, Sofia
Korte, Mechiel
Olivier, Berend
Garssen, J.
Kraneveld, Aletta D.
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Article
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Abstract
Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are neurodevelopmental disorders which occur in childhood and may persist into adulthood. Although the etiology of these disorders is largely unknown, genetic and environmental factors are thought to play a role in the development of ASD and ADHD. Allergic immune reactions, in prenatal and postnatal phases, are examples of these environmental factors, and adverse reactions to foods are reported in these children. In this review, we address the clinical and preclinical findings of (food) allergy in ASD and ADHD and suggest possible underlying mechanisms. Furthermore, opportunities for nutritional interventions in neurodevelopmental disorders are provided.
Keywords
Attention deficit hyperactivity disorder, Autism spectrum disorder, Food allergy, Food-based therapy, Gut-brain axis, Neurodevelopment, Immunology and Allergy, Pediatrics, Perinatology, and Child Health, Immunology
Citation
De Theije, C G M, Bavelaar, B M, Lopes da Silva, S, Korte, S M, Olivier, B, Garssen, J & Kraneveld, A D 2014, 'Food allergy and food-based therapies in neurodevelopmental disorders', Pediatric Allergy and Immunology, vol. 25, no. 3, pp. 218-226. https://doi.org/10.1111/pai.12149