Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission: A Cross-Sectional Study
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Publication date
2017-02-01
Authors
Huizinga, Pepijn
Kluytmans-Van Den Bergh, M
van Rijen, Miranda
Willemsen, Ina
van 't Veer, Nils
Kluytmans, Jan A.J.W.
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Document Type
Article
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taverne
Abstract
In this cross-sectional study, 8.5% of patients using proton pump inhibitors (PPIs) were rectal carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E), compared with 2.9% of non-PPI users. In multivariable analysis, PPI use was independently associated with ESBL-E rectal carriage at hospital admission (adjusted odds ratio, 3.89; 95% confidence interval, 1.65 - 9.19).
Keywords
Carriage, ESBL, Proton pump inhibitor, Risk factor, Taverne, Microbiology (medical), Infectious Diseases
Citation
Huizinga, P, van den Bergh, M K, van Rijen, M, Willemsen, I, van 't Veer, N & Kluytmans, J 2017, 'Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission : A Cross-Sectional Study', Clinical Infectious Diseases, vol. 64, no. 3, pp. 361-363. https://doi.org/10.1093/cid/ciw743