Severe transient neonatal long QT syndrome due to maternal paroxetine usage: a case report

Publication date

2019-10

Authors

Leerssen, Eeke C M
Tak, Ramon O
Breur, Johannes M P JISNI 0000000395622111

Editors

Advisors

Supervisors

Document Type

Article

Collections

Open Access logo

License

taverne

Abstract

A female neonate with in utero selective serotonin reuptake inhibitor exposure presented with bradycardia shortly after birth. Electrocardiography showed severe QT prolongation and second-degree atrioventricular block. Over time QT-times spontaneously normalised and genetic testing did not show mutations associated with long QT syndrome making maternal selective serotonin reuptake inhibitor usage the most likely explanation for the observed severe transient neonatal QT prolongation.

Keywords

Long QT syndrome, in utero exposure, neonate, paroxetine, selective serotonin reuptake inhibitor, Taverne, Cardiology and Cardiovascular Medicine, Pediatrics, Perinatology, and Child Health

Citation

Leerssen, E C M, Tak, R O & Breur, J M P J 2019, 'Severe transient neonatal long QT syndrome due to maternal paroxetine usage : a case report', Cardiology in the Young, vol. 29, no. 10, pp. 1300-1301. https://doi.org/10.1017/S1047951119001938