Updates to the CASP Infrastructure in 2024
Publication date
2026-01
Authors
Kryshtafovych, Andriy
Milostan, Maciej
Lensink, Marc F
Velankar, Sameer
Bonvin, Alexandre M J J
Moult, John
Fidelis, Krzysztof
Editors
Advisors
Supervisors
Document Type
Article
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License
cc_by
Abstract
CASP (critical assessment of structure prediction) conducts community experiments to determine the state of the art in calculating macromolecular structures. The CASP data management system is continually evolving to address the changing needs of the experiments. For CASP16, we expanded the infrastructure to enable data handling of newly introduced categories and fully support pilot categories introduced in CASP15. This technical note also documents the integration of the CASP and CAPRI (Critical Assessment of PRedicted Interactions) systems.
Keywords
3D structure prediction, CASP16, RNA structure, alternative conformations, protein structure, protein–ligand complexes, Structural Biology, Biochemistry, Molecular Biology
Citation
Kryshtafovych, A, Milostan, M, Lensink, M F, Velankar, S, Bonvin, A M J J, Moult, J & Fidelis, K 2026, 'Updates to the CASP Infrastructure in 2024', Proteins: Structure, Function and Genetics, vol. 94, no. 1, pp. 15-24. https://doi.org/10.1002/prot.70042