Mathematical analysis of the cellular immune reactions against tumor cells
Publication date
1985
Authors
Weger, R.A. de
Dullens, H.F.J.
Boer, R.J. de
Otter, W. den
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Advisors
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Document Type
Article
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Abstract
We have described a mathematical
model of interaction between T lymphocytes
and macrophages. In our model
two different types of cytotoxic effector
cells eradicate turnout cells: cytotoxic T
lymphocytes (CTL) and cytotoxic
macrophages. CTL are generated upon
recognition of antigenic determinants on
live, viable, tumour cells.