Mathematical analysis of the cellular immune reactions against tumor cells

Publication date

1985

Authors

Weger, R.A. de
Dullens, H.F.J.
Boer, R.J. de
Otter, W. den

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Article
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Abstract

We have described a mathematical model of interaction between T lymphocytes and macrophages. In our model two different types of cytotoxic effector cells eradicate turnout cells: cytotoxic T lymphocytes (CTL) and cytotoxic macrophages. CTL are generated upon recognition of antigenic determinants on live, viable, tumour cells.

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