How lymphocytes add up

Publication date

2016-12-16

Authors

Asquith, Becca
de Boer, Rob J.ORCID 0000-0002-2130-691XISNI 000000039525534X

Editors

Advisors

Supervisors

Document Type

Article
Open Access logo

License

taverne

Abstract

A surprising molecular mechanism underlying signal integration and programmed proliferation in adaptive immunity has been identified: the cell-cycle regulator Myc enables a lymphocyte to add up the strength of signals it receives and time its response accordingly.

Keywords

immune cell death, Lymphocyte Activation, T cells, Taverne

Citation

Asquith, B & de Boer, R J 2016, 'How lymphocytes add up', Nature Immunology, vol. 18, no. 1, pp. 12-13. https://doi.org/10.1038/ni.3636