Log In

A two-directional and highly convergent approach for the synthesis of the tumor-associated antigen Globo-H

Files

How and where to find an Open Access version of this publication?

Publication date

1999-12-03

Authors

Zhu, Tong
Boons, Geert-JanORCID 0000-0003-3111-5954ISNI 0000000120249047

Editors

Advisors

Supervisors

DOI

https://doi.org/10.1002/(SICI)1521-3773(19991203)38:23<3495::AID-ANIE3495>3.0.CO;2-X

Document Type

Article

Metadata

Show full item record

Collections

Utrecht University Repository

License

Abstract

The assembly of six readily available building blocks in five glycosylation steps affords the tumor-associated Globo-H hexasaccharide 1 without the need for any intermediate protecting group manipulations. The aminopropyl spacer is employed for conjugation to carrier proteins.

Keywords

Antigens, Chemoselectivity, Glycosylations, Oligosaccharides, General Chemistry

Citation

Zhu, T & Boons, G J 1999, 'A two-directional and highly convergent approach for the synthesis of the tumor-associated antigen Globo-H', Angewandte Chemie - International Edition, vol. 38, no. 23, pp. 3495-3497. https://doi.org/10.1002/(SICI)1521-3773(19991203)38:23<3495::AID-ANIE3495>3.0.CO;2-X

URI

http://hdl.handle.net/1874/379327