Plasmids of distinct IncK lineages show compatible phenotypes

Publication date

2017-03

Authors

Rozwandowicz, MartaISNI 0000000526348344
Brouwer, MichaelORCID 0000-0002-1067-7555
Zomer, Aldert L.ORCID 0000-0002-0758-5190ISNI 0000000393481634
Bossers, Alex
Harders, Frank
Mevius, Dik JISNI 0000000394318601
Wagenaar, Jaap AISNI 0000000388430808
Hordijk, JoostISNI 0000000419441826

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Document Type

Article
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Abstract

IncK plasmids are one of the main carriers of bla CTX-M-14 and bla CMY-2 genes and show high similarity to other plasmids belonging to the I complex, including IncB/O plasmids. Here, we studied the phylogenetic relationship of 37 newly sequenced IncK and IncB/O plasmids. We show that IncK plasmids can be divided into two compatible lineages named IncK1 and IncK2.

Keywords

IncK, Incompatibility, Plasmid

Citation

Rozwandowicz, M, Brouwer, M S M, Zomer, A L, Bossers, A, Harders, F, Mevius, D J, Wagenaar, J A & Hordijk, J 2017, 'Plasmids of distinct IncK lineages show compatible phenotypes', Antimicrobial Agents and Chemotherapy, vol. 61, no. 3, e01954-16. https://doi.org/10.1128/AAC.01954-16