Within-Household Transmission and Bacterial Diversity of Staphylococcus pseudintermedius.
Publication date
2022-08
Authors
Wegener, Alice
Duim, Birgitta
van der Graaf-van Bloois, Linda
Zomer, Aldert L
Visser, Caroline E
Spaninks, Mirlin
Timmerman, Arjen J
Wagenaar, Jaap A
Broens, Els M
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
cc_by
Abstract
Staphylococcus pseudintermedius can be transmitted between dogs and their owners and can cause opportunistic infections in humans. Whole genome sequencing was applied to identify the relatedness between isolates from human infections and isolates from dogs in the same households. Genome SNP diversity and distribution of plasmids and antimicrobial resistance genes identified related and unrelated isolates in both households. Our study shows that within-host bacterial diversity is present in S. pseudintermedius, demonstrating that multiple isolates from each host should preferably be sequenced to study transmission dynamics.
Keywords
S. pseudintermedius, transmission, One health, whole genome sequencing, zoonotic, bacterial diversity
Citation
Wegener, A, Duim, B, van der Graaf-van Bloois, L, Zomer, A L, Visser, C E, Spaninks, M, Timmerman, A J, Wagenaar, J A & Broens, E M 2022, 'Within-Household Transmission and Bacterial Diversity of Staphylococcus pseudintermedius.', Pathogens, vol. 11, no. 8, 850, pp. 1-6. https://doi.org/10.3390/pathogens11080850