Effectiveness of Vaccines and Monoclonal Antibodies Against Respiratory Syncytial Virus: Generic Protocol for Register-Based Cohort Study

Publication date

2024-03-15

Authors

Poukka, Eero
Roekel, Caren van
Turunen, Topi
Baum, Ulrike
Kramer, Rolf
Begier, Elizabeth
Presser, Lance D.
Teirlinck, Anne
Heikkinen, Terho
Knol, Mirjam

Editors

Advisors

Supervisors

Document Type

Article

Collections

Open Access logo

License

taverne

Abstract

Several immunization products are currently being developed against respiratory syncytial virus (RSV) for children, pregnant females, and older adults, and some products have already received authorization. Therefore, studies to monitor the effectiveness of these products are needed in the following years. To assist researchers to conduct postmarketing studies, we developed a generic protocol for register-based cohort studies to evaluate immunization product effectiveness against RSV-specific and nonspecific outcomes. To conduct a study on the basis of this generic protocol, the researchers can use any relevant databases or healthcare registers that are available at the study site.

Keywords

maternal immunization, monoclonal antibody, respiratory syncytial virus, RSV, vaccine, Taverne, General Medicine

Citation

Poukka, E, Roekel, C V, Turunen, T, Baum, U, Kramer, R, Begier, E, Presser, L D, Teirlinck, A C, Heikkinen, T, Knol, M, Nohynek, H, Bont, L & PROMISE investigators 2024, 'Effectiveness of Vaccines and Monoclonal Antibodies Against Respiratory Syncytial Virus : Generic Protocol for Register-Based Cohort Study', Journal of Infectious Diseases, vol. 229, pp. S84-S91. https://doi.org/10.1093/infdis/jiad484