Update to RIFM fragrance ingredient safety assessment, methyl cyclohexadiene (mixture of isomers), CAS Registry Number 30640-46-1

Publication date

2025-12

Authors

Api, A. M.
Bartlett, A.
Belsito, D.
Botelho, D.
Bruze, M.
Bryant-Friedrich, A.
Burton, G. A.
Cancellieri, M. A.
Chon, H.
Cronin, M.

Editors

Advisors

Supervisors

Document Type

Article
Open Access logo

License

taverne

Abstract

• Methyl cyclohexadiene (mixture of isomers); a safety assessment based on RIFM's criteria.• A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

Keywords

Taverne, Food Science, Toxicology, SDG 3 - Good Health and Well-being

Citation

Api, A M, Bartlett, A, Belsito, D, Botelho, D, Bruze, M, Bryant-Friedrich, A, Burton, G A, Cancellieri, M A, Chon, H, Cronin, M, Crotty, S, Dagli, M L, Dekant, W, Deodhar, C, Farrell, K, Fryer, A D, Jones, L, Joshi, K, Lapczynski, A, Laskin, D L, Lavelle, M, Lee, I, Moustakas, H, Muldoon, J, Penning, T M, Piersma, A H, Ritacco, G, Sadekar, N, Schember, I, Schultz, T W, Siddiqi, F, Sipes, I G, Sullivan, G & Thakkar, Y 2025, 'Update to RIFM fragrance ingredient safety assessment, methyl cyclohexadiene (mixture of isomers), CAS Registry Number 30640-46-1', Food and Chemical Toxicology, vol. 206, 115765, pp. 1-10. https://doi.org/10.1016/j.fct.2025.115765