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Systemic Light Chain Amyloidosis

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978-3-031-44080-9_82.pdf (329.87 KB)

Publication date

2024-04-11

Authors

Minnema, MoniqueORCID 0000-0002-3139-8379ISNI 0000000394782842
Schönland, Stefan

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DOI

https://doi.org/10.1007/978-3-031-44080-9_82

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Part of book

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Abstract

Systemic light chain (AL) amyloidosis is a rare protein misfolding and deposition disorder. Clonal plasma cells or rarely B cells produce immunoglobulin light chains with the potential to misfold. Treatment is clone directed with the goal to achieve a complete or at least very good hematological remission. AutoHCT is an option in a selected group of patients. Results from cellular therapies are encouraging and will play an important role in the future.

Keywords

General Medicine

Citation

Minnema, M & Schönland, S 2024, Systemic Light Chain Amyloidosis. in The EBMT Handbook : Hematopoietic Cell Transplantation and Cellular Therapies. Springer, pp. 751-755. https://doi.org/10.1007/978-3-031-44080-9_82

URI

https://dspace.library.uu.nl/handle/1874/457199