Clinical Trial Registration Patterns and Changes in Primary Outcomes of Randomized Clinical Trials From 2002 to 2017
Publication date
2022-05-16
Authors
Lamberink, Herm
Vinkers, Christiaan H.
Lancee, Michelle
Damen, Johanna A A G
Bouter, Lex M
Otte, Willem M.
Tijdink, Joeri K
Editors
Advisors
Supervisors
Document Type
Letter
Metadata
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taverne
Abstract
This cross-sectional study evaluates the existence and timing of trial registration for randomized clinical trials (RCTs) published from 2002 to 2017 as well as substantive changes to the primary outcomes entered into registry information after those studies started.
Keywords
Humans, Randomized Controlled Trials as Topic, Registries, Taverne, Journal Article, Research Support, Non-U.S. Gov't
Citation
Lamberink, H J, Vinkers, C H, Lancee, M, Damen, J A A, Bouter, L M, Otte, W M & Tijdink, J K 2022, 'Clinical Trial Registration Patterns and Changes in Primary Outcomes of Randomized Clinical Trials From 2002 to 2017', JAMA Internal Medicine, vol. 182, no. 7, pp. 779-782. https://doi.org/10.1001/jamainternmed.2022.1551