Log In

Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity

Files

How and where to find an Open Access version of this publication?

Publication date

2013-10-03

Authors

Geijsen, NielsISNI 0000000396192432

Editors

Advisors

Supervisors

DOI

https://doi.org/10.1016/j.stem.2013.09.011

Document Type

Article

Metadata

Show full item record

Collections

Utrecht University Repository

License

Abstract

Human embryonic stem cells (hESCs) are hypersensitive to apoptotic stimuli, though the underlying mechanisms are poorly characterized. In this issue of Cell Stem Cell, Liu et al. (2013) report that mitochondria of human ESCs exist in an apoptosis-prone state, ready to act as cellular executioners upon detecting DNA damage.Copyright © 2013 Elsevier Inc. All rights reserved.

Keywords

Citation

Geijsen, N 2013, 'Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity', Cell Stem Cell, vol. 13, no. 4, pp. 371-372. https://doi.org/10.1016/j.stem.2013.09.011

URI

http://hdl.handle.net/1874/290131