Developing technologies to assess vascular ageing: a roadmap from VascAgeNet
Publication date
2024-12-01
Authors
Zanelli, Serena
Agnoletti, Davide
Alastruey, Jordi
Allen, John
Bianchini, Elisabetta
Bikia, Vasiliki
Boutouyrie, Pierre
Bruno, Rosa Maria
Climie, Rachel
Djamaleddine, Djeldjli
Editors
Advisors
Supervisors
Document Type
Article
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Abstract
Vascular ageing (vascular ageing) is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.
Keywords
ageing, arterial stiffness, blood pressure, cardiovascular, commercialisation, prevention, pulse wave velocity, Journal Article
Citation
Zanelli, S, Agnoletti, D, Alastruey, J, Allen, J, Bianchini, E, Bikia, V, Boutouyrie, P, Bruno, R M, Climie, R, Djamaleddine, D, Gkaliagkousi, E, Giudici, A, Gopcevic, K, Grillo, A, Guala, A, Hametner, B, Joseph, J, Karimpour, P, Kodithuwakku, V, Kyriacou, P A, Lazaridis, A, Lonnebakken, M T, Martina, M R, Mayer, C C, Nabeel, P M, Navickas, P, Nemcsik, J, Orter, S, Park, C, Pereira, T, Pucci, G, Amado Rey, A B, Salvi, P, Gonçalves Seabra, A C, Seeland, U, van Sloten, T, Spronck, B, Stansby, G, Steens, I, Stieglitz, T, Tan, I, Veerasingam, D, Wassertheurer, S, Weber, T, Westerhof, B E & Charlton, P H 2024, 'Developing technologies to assess vascular ageing : a roadmap from VascAgeNet', Physiological Measurement, vol. 45, no. 12, 121001. https://doi.org/10.1088/1361-6579/ad548e