Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs
Publication date
2019-10
Authors
Slenter, Inge J.M.
Djajadiningrat-Laanen, Sylvia C.
de Vries, Irma
Dijkman, Marieke
Editors
Advisors
Supervisors
Document Type
Article
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cc_by_nc_nd
Abstract
We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of Ornithogalum plant material can be potentially life-threatening to companion animals. Further studies are necessary to confirm the involvement of cardiac glycoside-like toxins present in Ornithogalum arabicum and the toxicity of these substances to the retina.
Keywords
Blindness, Cardiac glycosides, Ornithogalum arabicum, Retinal degeneration, Toxicology
Citation
Slenter, I J M, Djajadiningrat-Laanen, S C, de Vries, I & Dijkman, M A 2019, 'Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs', Toxicon X, vol. 4, 100014. https://doi.org/10.1016/j.toxcx.2019.100014