Biological Functions and Clinical Applications of Anti-Müllerian Hormone in Stallions and Mares
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Publication date
2016
Authors
Claes, Anthony N.
Ball, Barry A
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Supervisors
Document Type
Article
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taverne
Abstract
Anti-Müllerian hormone (AMH) plays a major role in sexual differentiation, Leydig cell differentiation, and folliculogenesis. In addition, AMH has clinical value in equine practice. In stallions, AMH can serve as an endocrine marker for equine cryptorchidism and as an immunohistochemical marker for Sertoli cell tumors. Considering that AMH is also an ovarian specific product, intact mares can be differentiated from ovariectomized mares. Peripheral AMH concentrations reflect the follicular population in mares, and therefore, are useful in the assessment of ovarian reserve and reproductive life-span of aged mares. Last, AMH is particular suitable as diagnostic marker for equine granulosa cell tumors.
Keywords
Anti-Müllerian hormone, Equine, Mare, Stallion, Cryptorchidism, Sertoli cell tumor, Ovarian reserve, Equine granulosa cell tumor, Taverne
Citation
Claes, A N J & Ball, B A 2016, 'Biological Functions and Clinical Applications of Anti-Müllerian Hormone in Stallions and Mares', Veterinary Clinics of North America-Equine Practice, vol. 32, no. 3, pp. 451–464. https://doi.org/10.1016/j.cveq.2016.07.004