Bringing online adaptive radiotherapy to a standard C-arm linac
Publication date
2024-07
Authors
Groot Koerkamp, Maureen
Bol, G H
Kroon, Petra S
Krikke, Lean L.
Harderwijk, Tessa
Zoetelief, Annelies J.
Scheeren, Annick
van der Vegt, Stefan
Plat, Annika
Hes, Jochem
Editors
Advisors
Supervisors
Document Type
Article
Metadata
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Abstract
Current online adaptive radiotherapy (oART) workflows require dedicated equipment. Our aim was to develop and implement an oART workflow for a C-arm linac which can be performed using standard clinically available tools. A workflow was successfully developed and implemented. Three patients receiving palliative radiotherapy for bladder cancer were treated, with 33 of 35 total fractions being delivered with the cone-beam computed tomography (CBCT)-guided oART workflow. Average oART fraction duration was 24 min from start of CBCT acquisition to end of beam on. This work shows how oART could be performed without dedicated equipment, broadening oART availability for application at existing treatment machines.
Keywords
Bladder cancer, Cone-beam computed tomography, Image-guided radiotherapy, Linear accelerator, Online adaptive radiotherapy (oART), Radiation, Oncology, Radiology Nuclear Medicine and imaging
Citation
Groot Koerkamp, M L, Bol, G H, Kroon, P S, Krikke, L L, Harderwijk, T, Zoetelief, A J, Scheeren, A, van der Vegt, S, Plat, A, Hes, J, van Gasteren, I B A, Renders, E R T, Rutgers, R H A, Kok, S W, van Kaam, J, Schimmel-de Kogel, G J, Sikkes, G G, Winkel, D, van Rijssel, M J, Wopereis, A J M, Ishakoglu, K, Noteboom, J L, van der Voort van Zyp, J R N, Beck, N, Soeterik, T F W, van de Pol, S M G, Eppinga, W S C, van Es, C A & Raaymakers, B W 2024, 'Bringing online adaptive radiotherapy to a standard C-arm linac', Physics and Imaging in Radiation Oncology, vol. 31, 100597. https://doi.org/10.1016/j.phro.2024.100597