Complete follicular development and recovery of ovarian function of frozen-thawed, autotransplanted caprine ovarian cortex

Publication date

2009-04

Authors

Santos, Regiane R
Knijn, H.M.ISNI 0000000391628823
Vos, PeterISNI 0000000364110949
Oei, Christine H.Y.ISNI 0000000492915047
van Loon, ThijsISNI 000000039362771X
Colenbrander, Ben
Gadella, B.M.ISNI 0000000395892373
van den Hurk, Rob
Roelen, BernardISNI 0000000368939906

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Supervisors

Document Type

Article
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Abstract

Frozen-thawed ovarian cortical fragments (1 mm(3)) were autotransplanted to the uterus of completely ovariectomized goats. The grafts developed preovulatory follicles, accompanied by estrous behavior and a rise in plasma E(2) levels, demonstrating successful cryopreservation and transplantation.

Keywords

Animals, Cryopreservation, Estrogens, Estrus, Female, Goats, Models, Animal, Ovarian Follicle, Ovariectomy, Ovary, Progesterone, Testosterone, Transplantation, Autologous

Citation

Santos, R R, Knijn, H M, Vos, P L A M, Oei, C H Y, van Loon, T, Colenbrander, B, Gadella, B M, van den Hurk, R & Roelen, B A J 2009, 'Complete follicular development and recovery of ovarian function of frozen-thawed, autotransplanted caprine ovarian cortex', Fertility and Sterility, vol. 91, no. 4 Suppl, pp. 1455-1458. https://doi.org/10.1016/j.fertnstert.2008.07.018