Severity of Respiratory Infections With Seasonal Coronavirus Is Associated With Viral and Bacterial Coinfections
Publication date
2021-01
Authors
de Koff, Emma M
van Houten, Marlies
Sanders, Lieke
Bogaert, Debby
Editors
Advisors
Supervisors
Document Type
Article
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taverne
Abstract
The clinical presentation of human coronavirus (HCoV) infections in children varies strongly. We show that children with an HCoV-associated lower respiratory tract infection more frequently had respiratory syncytial virus codetected and higher abundance of Haemophilus influenzae/haemolyticus than asymptomatic HCoV carriers as well as children with a non-HCoV-associated lower respiratory tract infection. Viral and bacterial cooccurrence may drive symptomatology of HCoV-associated infections including coronavirus disease 2019.
Keywords
SARS-CoV-2, coinfection, coronaviruses, lower respiratory tract infection, pediatrics, Taverne, Pediatrics, Perinatology, and Child Health, Microbiology (medical), Infectious Diseases
Citation
de Koff, E M, van Houten, M A, Sanders, E A M & Bogaert, D 2021, 'Severity of Respiratory Infections With Seasonal Coronavirus Is Associated With Viral and Bacterial Coinfections', The Pediatric infectious disease journal, vol. 40, no. 1, pp. e36-e39. https://doi.org/10.1097/INF.0000000000002940