ESTRO consensus guidelines on GTV delineation and dose-escalation in rectal cancer
Publication date
2026-05
Authors
Chiloiro, Giuditta
Romano, Angela
Beets-Tan, Regina
Bujko, Krzysztof
Cusumano, Davide
Fokas, Emmanouil
Haustermans, Karin
Huguet, Florence
Intven, Martijn Pw
Marijnen, Corrie AM
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Document Type
Article
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cc_by_nc_nd
Abstract
•Dose escalation, in rectal cancer, is defined as radiotherapy doses exceeding 54 Gy.•MRI-based GTV definition is central to dose-escalated rectal cancer RT.•Dose escalation supports organ preservation in selected rectal cancer patients.•Delphi methodology achieved consensus across key clinical and imaging domains.
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Journal Article
Citation
Chiloiro, G, Romano, A, Beets-Tan, R, Bujko, K, Cusumano, D, Fokas, E, Haustermans, K, Huguet, F, Intven, M P, Marijnen, C AM, Nacci, I, Nagtegaal, I D, Peters, F P, Stewart, A, Valentini, V & Gambacorta, M A 2026, 'ESTRO consensus guidelines on GTV delineation and dose-escalation in rectal cancer', Clinical and translational radiation oncology, vol. 58, 101131. https://doi.org/10.1016/j.ctro.2026.101131