High-Tech Drugs in Creaky Formulations

Publication date

2017-09

Authors

Herbrink, Maikel
Nuijen, Bastiaan
Schellens, JohannesISNI 0000000042971906
Beijnen, JosISNI 0000000140305595

Editors

Advisors

Supervisors

Document Type

Article
Open Access logo

License

taverne

Abstract

Recent literature reviews and registration documents covering novel Signal Transduction Inhibitors in the treatment of cancer paint a picture of inefficiency and variability, where formulation improvements could be valuable. In this article, we discuss apparent drug design flaws as we impose the current standard formulation practice.

Keywords

anticancer drugs, biopharmaceutics, formulation, pharmaceutics, Taverne, SDG 3 - Good Health and Well-being

Citation

Herbrink, M, Nuijen, B, Schellens, J H M & Beijnen, J H 2017, 'High-Tech Drugs in Creaky Formulations', Pharmaceutical Research, vol. 34, no. 9, pp. 1751-1753. https://doi.org/10.1007/s11095-017-2185-4