When observational studies are as helpful as randomized trials: Examples from orthopedic trauma: Examples from orthopedic trauma

Publication date

2019-09

Authors

Beks, R B
Bhashyam, Abhiram R.
Houwert, Roderick M.ISNI 0000000389377375
van der Velde, D
Van Heijl, M.
Smeeing, Diederik P.J.
Hietbrink, FalcoISNI 0000000388513355
Leenen, L. P.H.ORCID 0000-0001-8385-1801ISNI 0000000390070047
Groenwold, Rolf H.H.ISNI 0000000394374611

Editors

Advisors

Supervisors

Document Type

Article

Collections

Open Access logo

License

taverne

Abstract

Randomized controlled trials (RCTs) are often challenging to design in surgical fields and can be misleading when poorly executed. While the prevailing belief is that observational studies on therapeutic efficacy are credible only in exceptional circumstances due to unrecognized confounding, we identify three types of intervention in orthopaedic trauma and illustrate relevant features that allow observational studies in orthopaedic surgery to be as helpful as RCTs.

Keywords

Bone and Bones/injuries, Humans, Observational Studies as Topic, Orthopedic Procedures, Randomized Controlled Trials as Topic, Taverne, Critical Care and Intensive Care Medicine, Surgery, Journal Article

Citation

Beks, R B, Bhashyam, A R, Houwert, R M, van der Velde, D, van Heijl, M, Smeeing, D, Hietbrink, F, Leenen, L P H & Groenwold, R 2019, 'When observational studies are as helpful as randomized trials: Examples from orthopedic trauma : Examples from orthopedic trauma', The Journal of Trauma and Acute Care Surgery, vol. 87, no. 3, pp. 730-732. https://doi.org/10.1097/TA.0000000000002347